Two Glycerol-3-Phosphate Dehydrogenases from Chlamydomonas have Distinct Roles in Lipid Metabolism.[2017][Plant Physiol][10.1104pp.17.00491]

Two Glycerol-3-Phosphate Dehydrogenases from Chlamydomonas have Distinct Roles in Lipid Metabolism.[2017][Plant Physiol][10.1104pp.17.00491]

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大小:11.34 MB

页数:55页

时间:2017-06-26

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1、PlantPhysiologyPreview.PublishedonJune6,2017,asDOI:10.1104/pp.17.004911Runninghead:ChlamydomonasGlycerol-3-PhosphateDehydrogenases23Correspondingauthor:45DrJonPittman6SchoolofEarthandEnvironmentalSciences7FacultyofScienceandEngineering8TheUniversityofManchest

2、er9MichaelSmithBuilding10OxfordRoad11ManchesterM139PT,UK12Email:jon.pittman@manchester.ac.uk13Tel:+4416127552351415Researcharea:BiochemistryandMetabolism161DownloadedfromonJune17,2017-Publishedbywww.plantphysiol.orgCopyright©2017AmericanSocietyofPlantBiologis

3、ts.Allrightsreserved.Copyright2017bytheAmericanSocietyofPlantBiologists17TwoGlycerol-3-PhosphateDehydrogenasesfromChlamydomonashaveDistinct18RolesinLipidMetabolism19123420ThomasDriver,DrupadK.Trivedi,OwenA.McIntosh,AndrewP.Dean,23,21RoystonGoodacreandJonK.Pit

4、tman*22123FacultyofLifeSciences,TheUniversityofManchester,MichaelSmithBuilding,Oxford224Road,Manchester,M139PT,UK;ManchesterInstituteofBiotechnology,Schoolof25Chemistry,TheUniversityofManchester,131PrincessStreet,ManchesterM17DN,326UK;SchoolofEarthandEnvironm

5、entalSciences,FacultyofScienceandEngineering,27TheUniversityofManchester,MichaelSmithBuilding,OxfordRoad,ManchesterM134289PT,UK;SchoolofScienceandtheEnvironment,FacultyofScienceandEngineering,29ManchesterMetropolitanUniversity,ChesterStreet,Manchester,M15GD,U

6、K303132Summarysentence:Twoglycerol-3-phosphatedehydrogenasesfromChlamydomonas33arerequiredforstoragelipidaccumulationinresponsetonutrientstressbuthave34distinctmetabolicfunctions.352DownloadedfromonJune17,2017-Publishedbywww.plantphysiol.orgCopyright©2017Amer

7、icanSocietyofPlantBiologists.Allrightsreserved.36Footnotes:3738ThisworkwassupportedbyfundingfromtheBiotechnologyandBiologicalSciences39ResearchCouncilforaBBSRCDTPPhDstudentshiptoT.D.(grantnumber40BB/J014478/1)andaBBSRCDTPPhDstudentshiptoO.A.M.(grantnumber41BB

8、/M011208/1).MetabolomicsworkwassupportedbyBBSRCandBBSRC-42SYNBIOCHEMfundingtoR.G.(grantnumbersBB/C519038/1andBB/M017702/1).4344*Addresscorrespondencetojon.pittman@manchester.ac.uk4546Thea

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