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1、DissolutionMethodsListofallDrugsintheDatabaseDrugNameDosageFormUSPApparatusSpeed(RPMs)MediumVolume(mL)RecommendedSamplingTimes(minutes)DateUpdatedAbacavirSulfateTabletII(Paddle)750.1NHCl9005,10,15,and3003/22/2006AbacavirSulfate/LamivudineTabletII(Paddle)750.1NHCl90010,20,30,and4501/03/2
2、007AbacavirSulfate/Lamivudine/ZidovudineTabletII(Paddle)750.1NHCl9005,10,15,30,and4501/03/2007AcamprosateCalciumTablet(DelayedRelease)I(Basket)180AcidStage:0.1NHClBufferStage:"Citrate-sodiumhydroxide"bufferpH6.8(150mlof2NNaOH,21.014gmofcitricacidandultra-purewaterto1000ml)(MethodB)10001
3、20(Acid)30,60,90,120,and180(buffer)12/20/2005AcarboseTabletII(Paddle)75Water(deaerated)90010,15,20,30and4503/22/2006AcetaminophenSuppositoryII(Paddle)50Phosphatebuffer,pH590015,30,45,60and9008/17/2006AcetaminophenTablet(ExtendedRelease)RefertoUSP03/03/2011Acetaminophen/ButalbitalTabletI
4、I(Paddle)50Water(deaerated)90015,30,45,60and9001/03/2007TabletRefertoUSP01/14/2008Acetaminophen/Butalbital/CaffeineAcetaminophen/Butalbital/Caffeine/CodeinePhosphateCapsuleII(Paddle)50Water(deaerated)90010,20,30,45and6003/04/2006Acetaminophen/Caffeine/DihydrocodeineBitartrateTabletII(Pa
5、ddle)50Water90010,15,30,45,and6007/25/2007Acetaminophen/Caffeine/DihydrocodeineBitartrateCapsuleI(Basket)100Water90010,20,30,45and6001/03/2007Acetaminophen/HydrocodoneBitartrateTabletRefertoUSP07/25/2007Acetaminophen/OxycodoneTabletRefertoUSP01/14/2008Acetaminophen/PentazocineHClTabletI
6、(Basket)100Water(deaerated)90010,20,30,45and6001/12/2004Acetaminophen/PropoxypheneHClTabletRefertoUSP01/15/2010Acetaminophen/PropoxypheneNapsylateTabletRefertoUSP01/15/2010Acetaminophen/TramadolHClTabletII(Paddle)500.1NHCl9005,10,15,20and3003/04/2006AcetazolamideTabletRefertoUSP07/21/20
7、11AcetazolamideCapsule(ExtendedII(Paddle)75AcetateBuffer,pH4.5with2.2%Tween209001,2,5,7,9,12and14hours01/15/2010Release)AcetazolomideTabletRefertoUSP07/14/2008AcitretinCapsuleRefertoUSP09/22/2011Acrivastine/PseudoephedrineHClCapsuleII(Paddle)500.01NHCl9005,10,15and3001/12/2004A
