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1、SCI论文投稿coverletter投稿信模版DeareditorialboardofEuropeanJournalofCardiology,Pleasefindenclosedthemanuscript:“Theangiotensin-convertingenzymeisnotariskfactorformyocardialinfarctioninFrenchindividuals”,bySarahH.,etal.,tobesubmittedasaShortCommunicationtotheEuropean
2、JournalofNeurologyforconsiderationofpublication.Allco-authorshaveseenandagreewiththecontentsofthemanuscriptandthereisnofinancialinteresttoreport.Wecertifythatthesubmissionisoriginalworkandisnotunderreviewatanyotherpublication.Inthismanuscript,wereporttheresu
3、ltsofthefirststudyonthegeneticandfunctionalrolesoftheACEontheriskofsufferingamyocardialinfarctionintheFrenchpopulation.Indeed,wegenotypedthers4341polymorphismin531IScasesand549healthycontrols,andthenperformedfunctionalstudiesbymeasuringserumACEproteinlevelan
4、dactivityinhealthycontrols,strokepatientsatbaselineandstrokepatients24hafterstrokesymptomsonset.TheresultsfromourstudydidnotrevealanyassociationoftheACEvariantwithmyocardialinfarction,althoughitaffectedACEproteinlevel,andischemicstrokepatientsshowedlowerACEl
5、evelthancontrolsintheacutephasebutnotinthechronicphase.WebelievethatourfindingscouldbeofinteresttothereadersofEuropeanJournalofCardiologybecausetheybringnewandstrongevidencethattheACEgeneandproteinarenotariskfactorformyocardialinfarction.Wehopethattheeditori
6、alboardwillagreeontheinterestofthisstudy.Sincerelyyours,SarahH.onbehalfoftheauthors.Correspondingauthor:SarahHamiltonatCardiovascularResearchLaboratory,MarieCurieResearchInstitute,75000,Paris,France,xxx@mariecurie.fr,phonenumber:+33582246xxx,faxnumber:+33582
7、246xxx.Case1 DearEditor, Wewouldliketosubmittheenclosedmanuscriptentitled"GDNFAcutelyModulatesNeuronalExcitabilityandA-typePotassiumChannelsinMidbrainDopaminergicNeurons",whichwewishtobeconsideredforpublicationinNatureNeuroscience. GDNFhaslongbeenthoughttobe
8、apotentneurotrophicfactorforthesurvivalofmidbraindopaminergicneurons,whicharedegeneratedinParkinson’sdisease.Inthispaper,wereportanunexpected,acuteeffectofGDNFonA-typepotassiumchannels,leadingto