medical clinics of north america jan 2006 allergies and asthma外语英文电子书

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时间:2018-03-03

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1、ALLERGYCONTENTSPrefacexiAnthonyMontanaroGeneticsofAllergicDisease1JohnW.SteinkeandLarryBorishGeneticsprovidesthebasisforthehostresponsetoavarietyofenvironmentalfactorsthatcanresultincomplexgeneticdiseases,suchasasthmaandatopy.Anunderstandingofthegeneticbasisforthes

2、econditionsisessentialtounderstandtheirpathophysiol-ogy.Severalregionsofthehumangenomehavebeenreproduciblyassociatedwithasthmaandatopyandthefunctionaleffectsofthevariationintheseregionsarebeingelucidated.Itishopedthattheseandongoingstudieswillultimatelydefinenewtarg

3、etsforthenextgenerationofasthmaandallergytherapeutics.AllergicRhinitis:ImpactoftheDiseaseandConsiderationsforManagement17AlexanderN.GreinerAllergicrhinitisisacommonyetunderappreciatedinflammatoryconditionofthenasalmucosa.Thisarticlereviewscurrentconceptsofclassificat

4、ion,theimpactofthediseaseonqualityoflife,andas-sociatedconditionsandprovidesadetailedaccountofcurrentlyavailabletreatmentoptions.Asthma:DiagnosisandManagement39SameerK.MathurandWilliamW.BusseThediagnosisandmanagementofasthmacontinuetobeofcriticalimportance,asrecent

5、trendshavedemonstrateditsincreasingprevalence,morbidity,andperhapsmortality.Becausecurrenttreatmentsforasthmaareeffectiveandsafe,itisimportanttodiagnoseasthmaearlyandtousetreatmentseffectively,particu-larlythosedirectedtowardairwayinflammation.ThediagnosticVOLUME90Æ

6、NUMBER1ÆJANUARY2006viimeasuresandarrayofmedications,boththosecurrentlyavailableandonthehorizon,provideanarmamentariumforeffectivediag-nosis,management,andmonitoringofasthma.Incomingyears,itisexpectedthatadditionaltestingmodalitieswillbeavailableformoreprecisemonito

7、ringofasthmacontrol,andanincreasedunder-standingofpharmacogeneticswillenablethetailoringofasthmamedicationstospecificpatients,providingcustomizedtherapytomaximizeasthmacontrol.DifferentialDiagnosisofAdultAsthma61StephenA.TillesAsthmaisacommonsyndromethataffectsappro

8、ximately5%oftheadultpopulationintheUnitedStates.Thisarticlefocusesonthedifferentialdiagnosisofadultasthma,includingadiscussionofreasonableclinica

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《medical clinics of north america jan 2006 allergies and asthma外语英文电子书》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库

1、ALLERGYCONTENTSPrefacexiAnthonyMontanaroGeneticsofAllergicDisease1JohnW.SteinkeandLarryBorishGeneticsprovidesthebasisforthehostresponsetoavarietyofenvironmentalfactorsthatcanresultincomplexgeneticdiseases,suchasasthmaandatopy.Anunderstandingofthegeneticbasisforthes

2、econditionsisessentialtounderstandtheirpathophysiol-ogy.Severalregionsofthehumangenomehavebeenreproduciblyassociatedwithasthmaandatopyandthefunctionaleffectsofthevariationintheseregionsarebeingelucidated.Itishopedthattheseandongoingstudieswillultimatelydefinenewtarg

3、etsforthenextgenerationofasthmaandallergytherapeutics.AllergicRhinitis:ImpactoftheDiseaseandConsiderationsforManagement17AlexanderN.GreinerAllergicrhinitisisacommonyetunderappreciatedinflammatoryconditionofthenasalmucosa.Thisarticlereviewscurrentconceptsofclassificat

4、ion,theimpactofthediseaseonqualityoflife,andas-sociatedconditionsandprovidesadetailedaccountofcurrentlyavailabletreatmentoptions.Asthma:DiagnosisandManagement39SameerK.MathurandWilliamW.BusseThediagnosisandmanagementofasthmacontinuetobeofcriticalimportance,asrecent

5、trendshavedemonstrateditsincreasingprevalence,morbidity,andperhapsmortality.Becausecurrenttreatmentsforasthmaareeffectiveandsafe,itisimportanttodiagnoseasthmaearlyandtousetreatmentseffectively,particu-larlythosedirectedtowardairwayinflammation.ThediagnosticVOLUME90Æ

6、NUMBER1ÆJANUARY2006viimeasuresandarrayofmedications,boththosecurrentlyavailableandonthehorizon,provideanarmamentariumforeffectivediag-nosis,management,andmonitoringofasthma.Incomingyears,itisexpectedthatadditionaltestingmodalitieswillbeavailableformoreprecisemonito

7、ringofasthmacontrol,andanincreasedunder-standingofpharmacogeneticswillenablethetailoringofasthmamedicationstospecificpatients,providingcustomizedtherapytomaximizeasthmacontrol.DifferentialDiagnosisofAdultAsthma61StephenA.TillesAsthmaisacommonsyndromethataffectsappro

8、ximately5%oftheadultpopulationintheUnitedStates.Thisarticlefocusesonthedifferentialdiagnosisofadultasthma,includingadiscussionofreasonableclinica

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