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时间:2020-05-07
《同期手术治疗胃及结直肠肿瘤伴肝转移28例临床分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、结直肠肛门外科2014年第2O卷第1期同期手术治疗胃及结直肠肿瘤伴肝转移28例临床分析沈伯明俞卫君王永峰(复旦大学附属中山医院青浦分院外科上海201900)[摘要]目的探讨胃及结直肠肿瘤合并肝转移患者的手术治疗效果。方法2008年1月至2012年12月,32例伴肝转移的胃及结直肠肿瘤收治人院。对患者进行手术耐受性、手术切除可能性及手术风险评估。对于有手术指证并愿意接受手术的28例患者行手术治疗。胃肠道肿瘤根治术及肝转移灶切除术15例(其中2例行化疗泵植入术),胃及结直肠肿瘤切除术7例(其中2例行化疗泵植入术),胃空肠吻合术1例,结肠侧侧吻合术4例(其中行化
2、疗泵植入术2例),剖腹探查化疗泵植入术1例。术后化疗6个月,并终身随访。结果无手术死亡,术后3例出现腹腔积液,经置管引流后恢复良好,1例术后一周出现吻合口漏,予灌注冲洗低压持续引流两周后痊愈。术后肺部感染6例经抗感染治疗后痊愈,1例术后出现腹腔感染,经抗炎治疗后痊愈。一年生存率82.i,两年生存率42.9%,三年生存率25。结论胃肠道肿瘤合并肝转移并非手术绝对禁忌证,选择合适的患者,采取积极的外科手术治疗,可以获得较好的疗效。[关键词]胃肠道;肿瘤;肝转移;手术[中图分类号]R735.3[文献标志码]A[文章编号]1009—8771(2014)01—003
3、4—03OperationforthepatientsofgastricorcolorectalcarcinomawithlivermetastasisShenBoming,YuWeijun,WangYongfeng.(SurgicalDepartment,QingpuBranchofZhongShanHospital。ShangHai201700)[-Abstract]ObjectiveToinvestigatetheeffectsofoperationwiththepatientswhosufferedfromgastricorcolorectalca
4、rcinomawithlivermetastasis.MethodsFromJanuary2008toDecember2012,32casesofgas—tricorcolorectalcarcinomawithlivermetastasisadmittedinourdepartmentwereincluded.TheSurgerytoleranceofthepatientsandthepossibilityofsurgicalresectionofthesepatientswasassessed.Amongwhich28patientswhowithsu
5、rgicalindicationswereunderwentsurgery.Allofthemwereperformedchemotherapyanddidfollow—upevaluation.Results28casesinthisgroupwereperformedsurgeryand15casesofwhichwereperformedresectionofgastrointestinalcarcinomaandlivermetastasis(injectionin—strumentwasimplantedin2cases),and7caseswe
6、reunderwentgastrointestinalcarcinomaresectiononly(injectioninstrumentwasimplantedin2cases.Gastrojejunostomywasperformedin1case.4caseswereperformedcolocolicanastomosis(injectioninstrumentimplantedin2cases).Exploratorylaparotomyandsubcutaneousimplantablepumpwasdonein1case.Allofthems
7、urvivedaftersurgery.Pyoperitoneumoccurredin3caseswhichwerehealedbydraining.Anastomoticleakageoccurredin1casewhichhealedbylavationcleaningfortwoweeks.Pulmonaryinfectionwasoccurredin6caseswhileabdominalinfectionOC—curredin1casewhichwerehealedbyanti—infectivetherapy.One。twoandthreeye
8、arsurvivalratewere82.1,42.9and25。
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