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时间:2020-05-07
《北京市无偿献血人群病毒性肝炎的筛查结果分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、北京医学2014年第36卷第2期.临床输血专栏..论著.北京市无偿献血人群病毒性肝炎的筛查结果分析张莉袁曜高峰陈瑜高占冷婵孙莉葛红卫戴云刘江【摘要】目的分析北京市区无偿献ⅡIL者经传播HBV、HCV的血清学及核酸标志物的筛查情况,为无偿献血的招募策略调罄提供依据方法分析2007年1』{1日至2011年12月31日北京巾r宁『1fL液『_f1心无偿献Il『L者乙肝表面抗原(HBsAg)、丙型肝炎病毒(HCV)血清学及核酸的检测结果,按性别、年龄、职业、文化程度、献Iff【方式、献f『L组织形式进行分层.回顾性渊台分析各层5年之间的整
2、体情况结果2007—2011年5年问北京市红十字J1IL液巾心共有l065l77人次无偿献fl1=L.HBsAg和HCV筛查阳性率分别为0.36%、0.485%;男性的HBsAg携带率高于女性(P<0.05).但女性HCV的筛查阳性率明显高于男性(P<0.05),主要集巾存>/40岁、农民和高r1l以下文化程度组。献血者中2O~29岁年轻人所r比例最大.不同年龄组的筛查结果差异有统计学意义(P<0.05),HBsAg筛查阳性率随年龄增长而升高:除<20岁年龄组外(0.66%),HCV的筛查阳性率变化亦然..不同职业和义化程度献血人
3、群的阳性率之间差异均有统计学意义(P<0.05),农民的不合格率最高(0.48%,O.73%),高中以下人群的阳性率最高(0.44%,O.56%).不同组织形式无偿献血者的筛查结果间差异有统计学意义(P4、全。【关键词】无偿献血者病毒性肝炎筛查阳性率招募策略ScreeningofviralhepatitisinBeijingunpaidblooddonationZhangLi,YuanYao,GaoFeng,ChenYu,GaoZhan,LengChan,SunLi,GeHongwei,DaiYun,LiuJiang.DepartmentofBloodScreening,Be(jingRedCrossBloodCenter,Beijing100088,ChinaCorrespondingauthor:LiuJiang,Email:z5、hang—lid@163.com【Abstract】ObjectiveToprovidethebasisforadjustingrecruitingstrategyofunpaidblooddonors.MethodsSerologyandNATtestresultsofHBsAgandHCVofunpaiddonorsduringJan1st,2007toDec31th,2011inBeijingbloodcenterwereinvestigated,thenthegender,age,occupation,educationa6、llevel,wayofblooddonationandblooddona—tionorganizationformswascaMedoutretrospectively.Resultsl065177unpaiddonorsweretestedinthefiveyearsandthetotalpositiverateofserologicalandfor1NATofHBsAgandHCVwas0.360%and0.485%respectively.TherateofHBsAgcarrierofmalewasobviouslyhig7、herthanthefemaleandthatoftheHCVwaslowerfP<0.05).Thescreeningposi—tiverateofHCVinfemalewasmainlyinthe"40orelder."farmersand"underhighschoolgroups.ThepositiverateofHBsAgandHCVincreasedwiththegrowthofageexceptfor<20groupforHCV.and20~29agegroupaccountedforthelargestpropor8、tion.ThedifferenceofpositiverateofthetwohepatitistestingprojectsamongfiveprofessionalcrowdswasstatisticallysignificantfP<0.0
4、全。【关键词】无偿献血者病毒性肝炎筛查阳性率招募策略ScreeningofviralhepatitisinBeijingunpaidblooddonationZhangLi,YuanYao,GaoFeng,ChenYu,GaoZhan,LengChan,SunLi,GeHongwei,DaiYun,LiuJiang.DepartmentofBloodScreening,Be(jingRedCrossBloodCenter,Beijing100088,ChinaCorrespondingauthor:LiuJiang,Email:z
5、hang—lid@163.com【Abstract】ObjectiveToprovidethebasisforadjustingrecruitingstrategyofunpaidblooddonors.MethodsSerologyandNATtestresultsofHBsAgandHCVofunpaiddonorsduringJan1st,2007toDec31th,2011inBeijingbloodcenterwereinvestigated,thenthegender,age,occupation,educationa
6、llevel,wayofblooddonationandblooddona—tionorganizationformswascaMedoutretrospectively.Resultsl065177unpaiddonorsweretestedinthefiveyearsandthetotalpositiverateofserologicalandfor1NATofHBsAgandHCVwas0.360%and0.485%respectively.TherateofHBsAgcarrierofmalewasobviouslyhig
7、herthanthefemaleandthatoftheHCVwaslowerfP<0.05).Thescreeningposi—tiverateofHCVinfemalewasmainlyinthe"40orelder."farmersand"underhighschoolgroups.ThepositiverateofHBsAgandHCVincreasedwiththegrowthofageexceptfor<20groupforHCV.and20~29agegroupaccountedforthelargestpropor
8、tion.ThedifferenceofpositiverateofthetwohepatitistestingprojectsamongfiveprofessionalcrowdswasstatisticallysignificantfP<0.0
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