肠易激综合征患者直肠肛管测压的研究.doc

《肠易激综合征患者直肠肛管测压的研究.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、肠易激综合征患者直肠肛管测压的研究刘谦民郭荣斌郑文尧杨云生程留芳摘要：研究肠易激综合征(IBS)患者直肠肛管压力的变化。应用美国Sandhill公司提供的BIOLAB消化道压力检测仪及固态压力传感器导管,对43例明确诊断为IBS患者及20名正常人进行直肠肛管压力检测，观察各参数的改变。结果IBS患者腹泻组的FSV、DSV、DUSV、MTV均较正常对照组低，其中DSV.DUSV和MTV与对照组比较有显著性差异(P<0.01),便秘组的FSV、DSV、DUSV及MTV均较对照组高，其中FSV、DSV和DUSV和对照组比较有显著性差异(P<0.01)；IBS患者腹泻组的RRP、AR

2、P及MSQP较对照组高，ARPD较对照组低；便秘组的RRP、ARP及ARPD均较对照组高，MSQP较对照组低；ISB患者腹泻组、便秘组的ARIR量均高于对照组且有显著性差异(P<0.01)；IBS患者腹泻组的顺应性降低而便秘组的顺应性增高(P<0.01)o提示IBS患者的排便功能冇不同程度的异常。关键词：肠易激综合征；结肠疾病，功能性；直肠肛管测压分类号：R574.63文献标识码：AANORECTALMANOMETRYINIRRITABLEBOWELSYNDROMELiuQianmin(GeneralHospitalofPLA,Beijing100853)GuoRongbin

3、(GeneralHospitalofPLA,Beijing100853)ZhengWenyao(GeneralHospitalofPLA,Beijing100853)Abstract：Toinvestigatefecalcontinenceinpatientswithirritablebowelsyndrome(IBS),studieswereperformedin43patientswithIBSand20healthysubjects.AnorectalpressurewasmeasuredwithBioLABmonitorofdigestivetractandanore

4、ctalcatheterwithsolidstatemanometrictransducers.TheresultswereanalyzedbycomputationprogramsofAmericanSandhillCompany.Thesensationofdefecationvolume(DSV)’sensationofdefecationurgentvolume(DUSV)andmaximaltolerablevolume(MTV)inthepatientswithdiarrheapredominanttypeIBS(Dp-IBS)weresignificantlyl

5、owerthanhealthysubjects(P<0.01).Thefirstsensationvolume(FSV),DSVandDUSVinthepatientswithconstipationpredominanttypeIBS(Cp-IBS)weresignificantlyhigherthanhealthysubjects(P<0.01).Therectalrestingpressure(RRP)andanalrestingpressure(ARP)inpatientswithDp-IBSweresignificantlyhigherthanhealt

6、hysubjects(P<O.Ol).TheRRPandmaximalsqueezingpressure(MSQP)inthepatientswithDp-IBSweresign讦icantlyhigherthanhealthysubjects(P<0.01),andMSQPinthepatientswithCp-IBSwassignificantlylowerthanhealthysubjects(P<0.01).Therectianalinhibitoryreflex(RAIR)volumeinthepatientswithCp-IBSandDp-IBS

7、weresignificantlyhigherthanhealthysubjects(P<O.Ol).Therectalcomplianee(RC)inthepatientswithCp-IBSwassignificantlyhigherandthatinpatientswithDp-IBSwassignificantlylowerthanhealthysubjects(P<O.Ol).Theresultssuggestedtheabilityoffecalcontinenceinthepa