《epilepsy癫痫》ppt课件

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1、Chapter12.EpilepsyTHEFIRSTAFFILIATEDHOSPITAL,SUNYET-SENUNIVERSITYPROF.ZHOULIEMINlm_zhou2002@yahoo.com.cnKEYWORDS:Epilepsy(癫痫)EpilepticSeizure(癫痫发作)Electroencephalograph(EEG,脑电图)EpileptiformDischarge(痫性放电)AntiepilepticDrugs(抗癫痫药)EPILEPSYTheStressontheChapter:1.Tocomprehendtheepilepticdefiniti

2、on.2.Tounderstandandhaveagoodcommandofepilepsywithgeneralizedtonic-clonicseizure,absenceseizure,complexpartialseizureandJacksonianepilepsy.WestsyndromeandLennox-Gastautsyndrome.3.Tounderstandandhaveagoodcommandofepilepticdiagnoses4.Tounderstandandhaveagoodcommandofdistinguishingbetweengenera

3、lizedtonic-clonicseizureandhysteria,absenceseizureandsyncope.5.Tounderstandandhaveagoodcommandofdefinitionandtreatmentprincipleonstatusepilepsywithgeneralizedtonic-clonicseizure.6.Tocomprehendtheprincipleinusingantiepilepticdrugs.RonaldoVincentvanGoghSeizureEpilepsyEpilepticSeizureEpilepsyis

4、characterizedbywhichsuddenrecurrentandtransientdisturbancesofmentalfunctionormovementsandsenseofthebodyareresultedfromabnormalneuronaldischargesinbrain.(usedto)Part1.DEFINITIONEpilepsyisadisorderofthebraincharacterizedbyanenduringpredispositiontogenerateepilepticseizuresandbytheneurobiologic

5、,cognitive,psychological,andsocialconsequencesofthiscondition.Thedefinitionofepilepsyrequirestheoccurrenceofatleastoneepilepticseizure.(newconcept)OUTLINE:Course:therecurrenceofepilepticseizuresLocation:usuallyarisingfromthecerebralcortexPathogenesis:abnormalneuronaldischargesClinicalsig

6、ns:transientdisturbancesofcerebralfunctionPart1.DEFINITIONPart2.ATIOLOGYANDBASICMECHANISMSOFEPILEPTOGENESIS,THEINDUCINGELEMENTSSymptomatic.CongenitaldiseasesStructuralLesionoftheBrain:Epilepsy.Braintrauma1.Remarkabledecreaseinthe.InfectionofCNsynapticfromGABA..Braintumor2.Disorderofblood-bra

7、inbarrier.CerebrovascularDBiochemicalAspects:Decrease.DegenrativeDinsyntheticGABAandincrease.Toxicosisinexcitatorytransmitter..NutritiveandElectrophysiologicalAspects:metabolicdisturbanceParoxysmaldepolarization.Theothersshift(PDS)discoveredAtiolog