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ID:39695745
大小:2.24 MB
页数:58页
时间:2019-07-09
《2- Multi-Effect-Coupling pH-Stimulus (MECpH) Model for pH-Sensitive Hydrogel》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、Chapter2Multi-Effect-CouplingpH-Stimulus(MECpH)ModelforpH-SensitiveHydrogel2.1IntroductionIngeneral,thedegreeofswelling/shrinkingofasmarthydrogelisdependentuponmanyeffects,suchastheionizablegroupandpolymericnetworkstructureofthehydrogelandthecharacteristicsofenvironmentalsolutionsi
2、ncludingthecom-position,pHandtemperature,inwhichtherearedifferentinteractionsbetweenmechanical,chemicalandelectricalfields.Inthischapter,amultiphysicsmodelisdevelopedforsimulationoftheswelling/deswellingbehaviourofthehydrogelresponsivetosurroundingpHwhenthehydrogelisimmersedinthebuf
3、feredsolution,calledthemulti-effect-couplingpH-stimulus(MECpH)model.ThemodelisbasedonPoisson–Nernst–Planck(PNP)formulationandderivedincombinationwiththespeciesdiffusion,pendentionizablegroupdissociationreactionandelectricpotentialeffectforthedistributiveprofilesofionicconcentrations
4、andelectricpotentialwithinboththehydrogelandbathingsolutiondomainsinresponsetothechangeinpHofsurroundingsolution.ThePNPequationsarecoupledwithnonlinearmechanicalequilibriumgovern-ingequationforanalysisoflargedeformationofthepH-sensitivehydrogel.TheMECpHmodelisvalidatedbycomparisonb
5、etweenthesimulationresultsandpub-lishedexperimentdataavailableintheliterature.Itisfollowedbycomprehensiveparameterstudiesfortheinfluencesofhydrogelmaterialpropertiesandenviron-mentalsolutionsontheresponsiveperformanceofthepH-sensitivehydrogelwhenplacedinthebufferedsolution.2.2Develo
6、pmentoftheMECpHModelExtensivesearchofliteraturerevealsthatmostofthetheoreticalmodelsareeitheroversimplifiedtolimitapplicabilityortoocomplextoaccountflexiblyforsignifi-cantparametersrequestedbyexperiments.Therefore,theobjectiveofthissectionistoformulateatheoreticalmodelwithclearfundame
7、ntal,veryrobustnessandpossibleextensionforawiderangeofapplications.Thisisamultiphysicsmodelandtermedthemulti-effect-couplingpH-stimulus(MECpH)model.ItisdevelopedH.Li,SmartHydrogelModelling,DOI10.1007/978-3-642-02368-2_2,57CSpringer-VerlagBerlinHeidelberg2009582MECpHModelforpH-Sens
8、itiveHydrogelmathematicall
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