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时间:2019-06-25
《大鼠腹腔注射复方丹参注射液后血清中丹参素的测定_周陆怡》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中药药理与临床2013;29(4)113期随着训练天数的增加不断缩短;在空间探索实验中,覆盆子志,2010;30(10)∶1455~1457各给药组第一次穿越平台时间均有不同程度地缩短,各给药组2肖洪明,祖灵博,李石平,等.掌叶覆盆子化学成分的研究.中国药物穿越平台次数较模型组均有不同程度地增加,但以覆盆子全化学杂志,2011;21(6)∶220~2253MartinCitron.Alzheimer'sdisease:Strategiesfordiseasemodification.药、覆盆子氯仿部位、覆盆子乙酸乙酯部位作用有显著性差异。NatRe
2、vDrugDiscov.2010;(9)∶387~398因此,本次实验筛选出覆盆子有效部位为氯仿部位、乙酸乙酯4HogervorstE,CombrinckM,SmithAD.Testosteroneandgonado-tropin部位。与模型对照组相比较,覆盆子氯仿部位、乙酸乙酯部位组levelsinmenwithdementia.NeuroendocrinolLett,2003;24(3/4)∶203~血清睾酮水平明显增加,提示其改善大鼠学习记忆机制可能与208增加睾酮水平有关,其更深层次的机制有待于进一步探索。5HogervorstE,Lehm
3、annDJ,WardenDR,etal.ApolipoproteinEepsilon4andtestosteroneinteractintheriskofAlzheimer'sdiseaseinmen.IntJ参考文献GeriatrPsychiatry;2002,17(9)∶938~9401刘爽,张玉莲,周震.老年性痴呆流行病学研究进展.中国老年学杂Theimpactofraspberrydifferentextractpartsonkidney-YANGdeficiencyADrats'learningandmemoryabilitiesHuan
4、gLiping,XiongYujie,ZhaoMenglan,GongJiahua,XieYihui(JiangxiUniversityofTraditionalChineseMedicine,Nanchang330004)Objective:Tostudytheimpactofraspberrydifferentextractpartsonkidney-YANGdeficiencyADratscausedbyD-galactosejointhy-drocortisone,andscreeneffectivepartsofraspberry.Met
5、hods:RatswereintraperitonealinjectedwithD-galactoseindoseof12.5mg/100gforsixweeks.Allratswereintramuscularinjectedbyhydrocortisone2.5mg/100gforthelasttwoweeks,causingthekidney-YANGdeficien-cyADratsmodel.Theblankgroupandthemodelgroupweregivenagavageofsaline,whiletheothergroupsw
6、ereirrigatedpreventivelywithRaspberry'schloroformparts,n-botanolextract,ethylacetateextract,waterextractatthedoseof12g/kgfor4weeks.Therats'escapelaten-cy,spaceexplorationabilityintheMorriswatermazeandtherats'serumtestosteroneweredetected.Results:Comparedwithmodelgroup,Raspberr
7、y'sChloroformpartsandethylacetatepartscanshortentherats'escapelatencyandenhancetherats'spaceexplorationability,Whileserumtestosteronelevelissignificantlyincreased.Conclusion:Theeffectiveraspberry'sextractpartsinimprovingkidney-YANGdeficiencyADratslearningandmemoryabilitieswere
8、Chloroformpartsandethylacetatepart.Keywordsraspberrykidney-YA
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