不同工艺疏血通脉胶囊对小鼠凝血功能及血栓的形成影响

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1、171学校代码：10600学号：093058学位类型：专业学位广西中医药大学硕士学位论文不同工艺疏血通脉胶囊对小鼠凝血功能及血栓形成的影响研究生：林秋红导师：刘泰教授院系（部所）：第一临床医学院专业：中西医结合临床研究方向：脑血管病的中西医防治完成日期：2012年06月05日目录中文摘要·················································3英文摘要·················································5引言····

2、·················································8正文·····················································91实验材料···············································91.1实验动物及饲养条件····································91.2试验药物·······································

3、·······91.3主要试剂及仪器·······································102试验方法〃··············································102.1动物分组·············································102.2动物给药·············································112.3血栓模型的制备·······················

4、················112.4检测方法·············································122.5统计方法·············································123实验结果···············································134讨论···················································164.1疏血通脉方的中西医理论探源··

5、·························164.2疏血通脉方的方义药性分析·····························194.3血栓形成机制·········································204.4方中各味药对凝血及抗血栓影响的研究···················234.5关于三七的提取工艺···································264.6本实验动物的选择原则··························

6、·······294.7试验结果分析·········································315存在的问题和展望·······································331结论····················································34参考文献·················································35附录·····························

7、·······················40综述····················································41致谢····················································54攻读学位期间发表的学术论文目录···························55作者声明·················································55个人简历··············

8、···································562中文摘要目的观察不同工艺疏血通脉胶囊对小鼠凝血功能及血栓形成的影响，以明确疏血通脉胶囊的最佳制作工艺。方法1、凝血试验：取雄性小鼠110只，随机分11组，每组10只，分别为生理盐水组、曲克芦丁组、疏血通脉胶囊Ⅰ号、Ⅱ号、Ⅲ号组（各组再分为低、中、高剂量三个亚组）。灌胃给药7日，每日1次。①玻片法：末次给药1h后用毛细玻管于眼眶取血，滴于载玻片，立即用秒表记时。以针头