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1、单鼻孔经蝶入路外科治疗垂体瘤卒中疗效观察[摘要]目的:探讨单鼻孔经蝶入路外科治疗垂体瘤卒中的优点、治疗效果。方法:将患有垂体瘤且具有可比性的80例临床资料随机分为两组,每组40例,一组将其命名为经蝶组,即使用单鼻孔经蝶入路外科治疗垂体瘤卒中;另一组则命名为传统组,即使用传统的经颅手术治疗垂体瘤卒中。并观察手术情况,记录术中出血量、手术时间、住院时间以及术后随访观察记录有无尿崩症、脑脊液鼻漏等并发症的发生并进行总结比较分析。结果:80例垂体瘤患者都挺顺利的完成了手术。经蝶组的手术时间、住院时间比传统组短,术中出血量也比传统组少,另外脑脊液漏、尿崩症、视力恶化等并发症发生率也明显低于传统
2、组,差异具有统计学意义(P<0.05)。结论:单鼻孔经蝶入路外科治疗垂体瘤卒中技术简便、手术创伤小、安全性高、治疗效果好、术后恢复快、并发症少。[关键词]垂体肿瘤;单鼻孔经蝶入路;临床疗效Single-nostriltranssphenoidalroadsurgicaltreatmentofpituitaryapoplexyEfficacyofAbstractObjectivesExploretheadvantagesofasinglenostriltranssphenoidalsurgicaltreatmentofpituitaryapoplexy,thetherapeuticef
3、fect.MethodsSufferingfrompituitarytumorsandcomparable80casesclinicaldatawererandomlydividedintotwogroups,eachgroupof40cases,agroupnamedtranssphenoidalgroup,usingasinglenostriltranssphenoidalRoad,surgicaltreatmentofpituitarytumorapoplexy;agroupnamedforthetraditionalgroup,andthattheuseoftranscran
4、ialsurgicaltreatmentofpituitaryapoplexy.Andobservethesurgicalsituation,recordedintraoperativebloodloss,operativetime,hospitalstay,andpostoperativefollow-uptoobservetheoccurrenceoftherecordwithorwithoutthecomplicationsofdiabetesinsipidus,cerebrospinalfluidrhinorrhea,andasummaryofcomparativeanaly
5、sis.Results80casesofpituitarytumorpatientsallcametoasmoothcompletionofthesurgery.Butterflygroup,operativetime,hospitalstayisshorterthanthetraditionalgroup,intraoperativebloodlosswaslessthanthetraditionalgroup,additionofcerebrospinalfluidleakage,diabetesinsipidus,visualdeterioration,theincidence
6、ofcomplicationswassignificantlylowerthanthetraditionalgroup,thedifferencewassignificance(P<0.05).ConclusionsSingle-nostriltranssphenoidalsurgicaltreatmentofpituitaryapoplexytechnologyissimple,minimallyinvasive,safe,effectivetreatment,rapidpostoperativerecovery,fewercomplications.[Keywords]pitui
7、tarytumor;asinglenostriltranssphenoidal;clinicalefficacy垂体瘤通常又称为垂体腺瘤,是一种临床常见病,其发病率位居胶质瘤和脑膜瘤之后,其占颅内肿瘤的10%~15%,可引起诸如泌乳、男性乳房发育等内分泌症状并且很多脏器均可能受到损害。目前垂体腺瘤最主要也是最有效的方法就是用手术使肿瘤彻底清楚【1】。手术治疗垂体瘤的最终目的是保护正常垂体功能、解除其对神经组织的压迫以及消除内分泌症状。但随着医学水平的不断发