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时间:2020-05-09
《氨基末端脑钠肽和肌钙蛋白I联合检测在儿童肺炎并心力衰竭诊断中的应用.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、HainanMedJ,Jun.2015,Voi.26,No.12海南医学2015年6月第26卷第12期doi:10.3969~.issn.1003—6350.2015.12.0637氨基末端脑钠肽和肌钙蛋白I联合检测在儿童肺炎并心力衰竭诊断中的应用曾静好,赖永艺,丁永星(云浮市人民医院儿科,广东云浮527300)【摘要】目的探讨氨基末端脑钠肽(NT-pro.BNV)和肌钙蛋白I(cTnI)联合检测在儿童肺炎并心力衰竭诊断中的价值。方法选取儿童肺炎心衰、单纯肺炎和健康对照组各3O例,检测三组受试者的NT-pro.BNP、cTnI和心肌功能水平,并分析其关联性。结果肺
2、炎心衰组的左室射血分数(LEVF)、左室短轴缩短率(LVFS)明显低于单纯肺炎组和健康对照组,而cTnI、NT-proBNP水平明显高于另外两组(P≮O.05);cTIlI与LEVF、NT-pro.BNP与LEVF均呈负相关,而cTnI与NT-proBNP则呈正相关(尸3、炎心衰,灵敏度和可靠度均明显提高。【关键词】氨基末端脑钠肽;肌钙蛋白I;肺炎;心力衰竭【中图分类号】R725.6【文献标识码】A【文章编号】1003---6350(2015)12—1781—O3RoleofN-terminalpro-brainnatriureficpeptideandtroponinIinthediagnosisofchildrenwithpneumoniacomplicatedwithheartfailure.ZENGJing-hao,Lf4,y0—DINGYong-xing.DepartmentofPaediatrics,People"sHo4、spital,527300,Guangdong,CHINA【Abstract】ObjectiveToanalyzetheroleofN—terminalpro-brainnatriureticpeptide(NT-pro-SNe)andtro—poninI(cTrd)inthediagnosisofchildren、Ⅳimpneumoniacomplicatedwimheartfailure.MethodsThirtychildrenwitllpneumoniacomplicatedthheartfailure(groupA),30childrenonlywi也p5、neumonia(groupB),and30healthychildren(groupC)wererecruitedtodetectthelevelsofNT-pro—BNP,troponinI,andmyocardialfunctionTherele-vanceandvalueofthethreeindexeswereanalyzed.ResultsTheleftventricularejectionfraction(LEVF)andtheleftventricularfractionalshortening(LVFS)ofgroupAweresignifica6、ntlylowerthanthoseofgroupBandgroupC,whilecTrd,NT-pro-BNPlevelsofgroupAweresignificantlyhigherthanothertwogroups(P<0.05).cTnIandNT-pro—BNPwerebothnegativelycorrelatedmLEVF,whilecTnIandNT-pro—BNPshowedapositivecorelation(P7、FthanthosewithnegativecTnI(P8、prove
3、炎心衰,灵敏度和可靠度均明显提高。【关键词】氨基末端脑钠肽;肌钙蛋白I;肺炎;心力衰竭【中图分类号】R725.6【文献标识码】A【文章编号】1003---6350(2015)12—1781—O3RoleofN-terminalpro-brainnatriureficpeptideandtroponinIinthediagnosisofchildrenwithpneumoniacomplicatedwithheartfailure.ZENGJing-hao,Lf4,y0—DINGYong-xing.DepartmentofPaediatrics,People"sHo
4、spital,527300,Guangdong,CHINA【Abstract】ObjectiveToanalyzetheroleofN—terminalpro-brainnatriureticpeptide(NT-pro-SNe)andtro—poninI(cTrd)inthediagnosisofchildren、Ⅳimpneumoniacomplicatedwimheartfailure.MethodsThirtychildrenwitllpneumoniacomplicatedthheartfailure(groupA),30childrenonlywi也p
5、neumonia(groupB),and30healthychildren(groupC)wererecruitedtodetectthelevelsofNT-pro—BNP,troponinI,andmyocardialfunctionTherele-vanceandvalueofthethreeindexeswereanalyzed.ResultsTheleftventricularejectionfraction(LEVF)andtheleftventricularfractionalshortening(LVFS)ofgroupAweresignifica
6、ntlylowerthanthoseofgroupBandgroupC,whilecTrd,NT-pro-BNPlevelsofgroupAweresignificantlyhigherthanothertwogroups(P<0.05).cTnIandNT-pro—BNPwerebothnegativelycorrelatedmLEVF,whilecTnIandNT-pro—BNPshowedapositivecorelation(P7、FthanthosewithnegativecTnI(P8、prove
7、FthanthosewithnegativecTnI(P8、prove
8、prove
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