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时间:2020-04-24
《右美托咪定或芬太尼复合丙泊酚靶控输注在宫腔镜诊治中的对比观察-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·麻醉与镇痛·中国当代医药2014年6月第21卷第17期右美托咪定或芬太尼复合丙泊酚靶控输注在宫腔镜诊治中的对比观察姚杨城王诗庆张洁福建医科大学附属宁德市医院麻醉科.福建宁德352100【摘要】目的观察右美托咪定或芬太尼复合丙泊酚靶控输注用于宫腔镜手术的安全性和有效性。方法将择期行宫腔镜手术的90例患者随机分为D、F、N组,D组患者麻醉前10min内泵入右美托咪定0.5Ixg/kg.F组静脉注射芬太尼1~g/kg,N组注射生理盐水l0m1,注射完毕后即刻给予丙?白酚靶控输注,并根据手术刺激及患者反应调整靶浓度。观察3组患者麻醉前(To)、丙泊酚诱导完成后5min(T)及
2、术毕5min(T2)的平均动脉压(MAP)、心率(HR)、呼吸频率及血氧饱和度变化;记录丙泊酚总用量、手术时间、丙泊酚停止输注至患者呼唤睁眼时间:评价麻醉效果,苏醒后5min的视觉模拟评分(VAS)。结果D、F组患者的手术时间、苏醒时间明显短于N组,丙泊酚用量明显少于N组(P0.05)。3组患者的MAP、HRT、T2较T0明显降低(P3、,差异统计学意义(P>0.05):D、F组的麻醉效果及苏醒后5minVAS明显优于N组(P<0.05)。结论0.5kg右美托咪定或1p,g/kg芬太尼复合丙泊酚用于宫腔镜诊治手术较单纯应用丙泊酚更安全、有效。【关键词】右美托咪定;芬太尼;丙泊酚;靶控输注;宫腔镜手术【中图分类号】R614【文献标识码】A【文章编号】1674-4721(2014)06(b)一0096—03Comparisonofdexmedetomidineorfentanylcombinedwithpropofoltar-getcontrolledinfusioninthediagnosisandtre4、atmentofhysteroscopyYA0Yang-chengWANGShi—qingZHANGDepartmentofAnesthesiology,NingdeHospitalAfiliatedtoFujianMedicalUniversity,Ningde352100,China[Abstract]ObjectiveToevaluatethesafetyandeffectofdexmedetomidineorfentanylcombinedwithpropofoltargetcontrolledinfusioninthediagnosisandtreatment5、ofhysteroscopy.Methods90casesofpatientswhoweretakenhys·teroscopinsurgerywererandomlydividedintogroupD,FandN,0.5~s/kgdexmedetomidinewaspumpedintogroupDwithin10minbeforeanesthesia,1p,g/kgfentanylwasinjectedtogroupF,10mlnormalsalinewasinjectedtogroupN,propofoltargetcontrolledinfusionwasinst6、antlygiventothethreegroups,targetconcentrationwasadjustedaccordingtothesurgicalstimulationandpatientresponse.Themeanarterialpressure(MAP),heartrate(HR),respiratoryrateandoxy—gensaturationwasobservedbeforeanesthesia(rI10),5minafterthecompletionofpropofol-induced(T1)and5minaftersurgery(T2)7、;totalamountofpropofol,operationtime,timeofpropofolinfusiontothepatienttostopcallingeyeopeningwasrecorded;theeffectofanesthesia,5minafterawakeningvisualanalogscale(VAs)wasevaluated.ResultsTheoper.ationtime,recoverytimeingroupDandFwassignificantlyshorterthanthatingroupN,th
3、,差异统计学意义(P>0.05):D、F组的麻醉效果及苏醒后5minVAS明显优于N组(P<0.05)。结论0.5kg右美托咪定或1p,g/kg芬太尼复合丙泊酚用于宫腔镜诊治手术较单纯应用丙泊酚更安全、有效。【关键词】右美托咪定;芬太尼;丙泊酚;靶控输注;宫腔镜手术【中图分类号】R614【文献标识码】A【文章编号】1674-4721(2014)06(b)一0096—03Comparisonofdexmedetomidineorfentanylcombinedwithpropofoltar-getcontrolledinfusioninthediagnosisandtre
4、atmentofhysteroscopyYA0Yang-chengWANGShi—qingZHANGDepartmentofAnesthesiology,NingdeHospitalAfiliatedtoFujianMedicalUniversity,Ningde352100,China[Abstract]ObjectiveToevaluatethesafetyandeffectofdexmedetomidineorfentanylcombinedwithpropofoltargetcontrolledinfusioninthediagnosisandtreatment
5、ofhysteroscopy.Methods90casesofpatientswhoweretakenhys·teroscopinsurgerywererandomlydividedintogroupD,FandN,0.5~s/kgdexmedetomidinewaspumpedintogroupDwithin10minbeforeanesthesia,1p,g/kgfentanylwasinjectedtogroupF,10mlnormalsalinewasinjectedtogroupN,propofoltargetcontrolledinfusionwasinst
6、antlygiventothethreegroups,targetconcentrationwasadjustedaccordingtothesurgicalstimulationandpatientresponse.Themeanarterialpressure(MAP),heartrate(HR),respiratoryrateandoxy—gensaturationwasobservedbeforeanesthesia(rI10),5minafterthecompletionofpropofol-induced(T1)and5minaftersurgery(T2)
7、;totalamountofpropofol,operationtime,timeofpropofolinfusiontothepatienttostopcallingeyeopeningwasrecorded;theeffectofanesthesia,5minafterawakeningvisualanalogscale(VAs)wasevaluated.ResultsTheoper.ationtime,recoverytimeingroupDandFwassignificantlyshorterthanthatingroupN,th
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