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1、复合振动仪治疗骨质疏松对骨代谢影响的临床观察作者：作者：郑锦畅陈建庭裴卫卫【摘耍】冃的观察复合振动仪治疗骨质疏松(OP)对骨代谢的影响。方法70例OP志愿者随机分成复合振动组和对照组,每组35例。复合振动组采用自行研制的复合振动仪进行全身振动治疗，振动频率45〜55Hz,振动强度0.5〜0.8g,1次/隔天，30min/次，连续3个月，对照组不进行任何干预，于试验开始前3天、试验后第1、3个月分别检测各组碱性磷酸酶(ALP)、骨钙素(OC)、抗酒石酸酸性磷酸酶(TRAP)、钙磷乘积((Ca)X(P))的变化。结果第3个月，复合振动组的ALP、OC、TRAP、(Ca)X(
2、P)分别比试验前增加了44.6%、・9.4%、1.7%、7.5%,对照纽•的相应指标分别比试验前増加了22.8%、・13.3%、3.6%、4.7%,P值分别为0.108、0.788、0.606、0.171。结论复合振动仪治疗OP对骨代谢的影响无统计学意义，但骨代谢的绝对值有变化。【关键词】复合振动;骨质疏松;碱性磷酸酶滑钙素;抗酒石酸酸性磷酸酶;钙磷乘积ClinicalobservationofbonemetabolisminosteoporosispatientstreatedwithcompoundvibrationmachineZHENGJinChang,CHEN
3、JianTing,PEIWeiWei.DepartmentofOrthopaedicSurgeryandSpine,NanfangHospital,SouthernMedicalUniversity,Guangzhou510515,Guangdong,China[Abstract]ObjectiveToobservetheeffectofbonemetabolisminosteoporosis(OP)patientstreatedwithcompoundvibrationmachine・Methods70OPvolunteerswereselectedandwerera
4、ndomlydividedintowholebodycompoundvibrationtraininggroup(WBCV,n=35)andcontrolgroup(CON,n=35).ThepatientsinWBCVgrouptreatedwith3monthwholebodycompoundvibration(30min/d,Itime/qd,oscillationfrequency45〜55Hz,intensityofvibration0.5〜0.8g).ThepatientsinCONgroupweren'tgivenanytreatment,didnotpa
5、rticipateinanytraining,justkeepingthenormallifeasbefore・Alkalinephosphatase(ALP),osteocalcin(OC),tartrateresistanceacidphosphatase(TRAP)andcalciumphosphorusproductweremeasuredon3daysbeforeexperiment,1and3monthsafterexperiment.ResultsThelevelofALP,OCTRAP,(Ca)X(P)inWBCVgroupwasincreasedby
6、44.6%,-9.4%,1.7%and7.5%respectively.However,itwasincreaseby22.8%,-13.3%,3.6%and4.7%respectivelyinCONgroup(P=0.10&0.78&0606and0.171)・ConclusionsThewholebodycompoundvibrationtraininghasnoeffectonbonemetabolisminOP,whiletheabsolutevalueofbonemetabolismhasbeenchanged・[Keywords]Compoundvibrat
7、ion;Osteoporosis;Alkalinephosphatase(ALP);Osteocalcin(OC);Tartrateresistanceacidphosphatase(TRAP);Calciumphosphomsproduct((Ca)X(P))骨质疏松(OP)及OP性骨折是危害中老年健康的常见病，尤以绝经后妇女为其。临床上常采用夯物治疗抑制骨吸收或者促进骨形成，但商物大多存在副作用。近年来物理疗法(力学、电磁学)防治OP的研究成为热点(1〜4)。低于引起骨纽织损伤的机械振动信号具有很强的成骨效应，是一种新型治疗OP的模式
