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时间:2020-04-17
《不同麻醉和镇痛方法对老年患者非心脏手术术后早期认知功能的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、论著Lunzhu《中国医学创新》第11卷第25期(总第307~JJ)2014年9月不同麻醉和镇痛方法对老年患者非心脏手术术后早期认知功能的影响周丘①刘英①许方荣①【摘要1目的:探究不同麻醉和镇痛方法对老年患者非心脏手术术后早期认知功能的影响,为临床提供参考。方法:选取2012年6月一2013年12月来本院接受非心脏手术治疗的240例老年患者,按照随机数字表法将其分为全身麻醉静脉镇痛组和腰硬联合麻醉硬膜外镇痛组各120例,观察两组患者术后36h内的疼痛程度、神经精神功能以及术前、术后7d认知功能障碍的发生率。结果:两组术中的ECG、BP、HR、SpO,均
2、在正常范围,无显著差异;术后36h内,每隔12h进行1次的VAS评分结果显示,全身麻醉静脉镇痛组的镇痛效果均明显优于腰硬联合麻醉硬膜外镇痛组(P<0.05);通过两组手术期MMSE评分比较,腰硬联合麻醉硬膜外镇痛组术后12、24、36h的MMSE评分均明显高于全身麻醉静脉镇痛组(P<0.05);两组术前发生认知功能障碍的患者数量均为0,而腰硬联合麻醉硬膜外镇痛组术后7d认知功能障碍的发生率明显低于全身麻醉静脉镇痛组(P3、,以指导临床合理用药,减少术后不良反应的发生率。【关键词】麻醉;镇痛;老年患者;早期认知功能TheEffectofDifferentMethodsofAnesthesiaandAnalgesiaforNon—cardiacSurgeryonEarlyPostoperativeCognitiveFunctionofElderlyPatients/ZHOUQiu,LIUYing,XUFang-rong.//MedicalInnovationofChina,2014。11(25):010—012【Abstract】Objective:Toexplorethe4、ectofdifferentmethodsofanesthesiaandanalgesiafornon—eardiacsurgeryonearlypostoperativecognitivefunctionofelderlypatients,andprovideareferenceforclinicalpractice.Method:240elderlypatientswhoweretreatedwithnon—cardiacsurgeryfromJune2012toDecember2013inourhospitalwereselected,theyw5、ererandomlydividedintothegeneralanesthesiaanalgesiagroupandthecombinedspinalepiduralanesthesiaepiduralanalgesiagroup,120easesineachgroup.Thepainlevelsandneurologicalfunctionofpostoperativewithin36handthecognitivedysfunctionpreoperativeandpostoperativein7dbetweenthetwogroupswereo6、bserved.Result:TheECG,BP,HR,SpO2oftwogroupswereinthenormalrangeinoperation,nosignificantdifference.Postoperative36h,conductedVASscoreevery12h,theresultsshowedthatthegeneralanesthesiaanalgesiagroupweresignificantlybetterthanthecombinedspinalepiduralanesthesiaepiduralanalgesiagrou7、p(P<0.05).TheMMSEscoresincombinedspinalepiduralanesthesiaepiduralanalgesiagroupat12,24,36hweresignifieandyhigherthanthoseingeneralanesthesiaanalgesiagroup(P8、itivedysfunctionofcombinedspinalepiduralanesthe
3、,以指导临床合理用药,减少术后不良反应的发生率。【关键词】麻醉;镇痛;老年患者;早期认知功能TheEffectofDifferentMethodsofAnesthesiaandAnalgesiaforNon—cardiacSurgeryonEarlyPostoperativeCognitiveFunctionofElderlyPatients/ZHOUQiu,LIUYing,XUFang-rong.//MedicalInnovationofChina,2014。11(25):010—012【Abstract】Objective:Toexplorethe
4、ectofdifferentmethodsofanesthesiaandanalgesiafornon—eardiacsurgeryonearlypostoperativecognitivefunctionofelderlypatients,andprovideareferenceforclinicalpractice.Method:240elderlypatientswhoweretreatedwithnon—cardiacsurgeryfromJune2012toDecember2013inourhospitalwereselected,theyw
5、ererandomlydividedintothegeneralanesthesiaanalgesiagroupandthecombinedspinalepiduralanesthesiaepiduralanalgesiagroup,120easesineachgroup.Thepainlevelsandneurologicalfunctionofpostoperativewithin36handthecognitivedysfunctionpreoperativeandpostoperativein7dbetweenthetwogroupswereo
6、bserved.Result:TheECG,BP,HR,SpO2oftwogroupswereinthenormalrangeinoperation,nosignificantdifference.Postoperative36h,conductedVASscoreevery12h,theresultsshowedthatthegeneralanesthesiaanalgesiagroupweresignificantlybetterthanthecombinedspinalepiduralanesthesiaepiduralanalgesiagrou
7、p(P<0.05).TheMMSEscoresincombinedspinalepiduralanesthesiaepiduralanalgesiagroupat12,24,36hweresignifieandyhigherthanthoseingeneralanesthesiaanalgesiagroup(P8、itivedysfunctionofcombinedspinalepiduralanesthe
8、itivedysfunctionofcombinedspinalepiduralanesthe
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