卵巢癌SKOV3中Holoclone细胞的特性及其形成血管生成拟态的能力.pdf

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1、授予单位代码10089学号或中请号20122433H妗(i搿大？HebeiMedicalUniversity科学学位卵巢癌SKOV3中Holodone细胞的特性及其形成血管生成拟态的能力研究生：杨JL芬导师：吴小华教授专业：妇产科学二级学院：白求恩国际和平医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为

2、单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。、ri**.[y,y,脅研究生签名‘立

3、导师签章…二级学院领导盖章:及河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名為访导师签章-扣/r年目录中文摘要···············································

4、·····················································1英文摘要····································································································4英文缩写····································································································8研究论

5、文卵巢癌SKOV3中Holoclone细胞的特性及其形成血管生成拟态的能力前言····································································································9材料与方法······················································································10结果································

6、··································································20附图··································································································22附表·······························································································

7、···26讨论··································································································27结论··································································································29参考文献······················································

8、····································30综述肿瘤干细胞与血管生成拟态关系的研究····································33致谢··········································································································45个人简历··························································

9、········································46中文摘要卵巢癌SKOV3中Holoclone细胞的特性及其形成血管生成拟态的能力摘要目的：血管生成拟态（vasculogenicmimicry,VM）是高侵袭性的肿瘤细胞所具有的