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时间:2019-11-13
《米索前列醇联合硫酸镁治疗妊娠高血压综合征产后出血的疗效分析》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、米索前列醇联合硫酸镁治疗妊娠高血压综合征产后出血的疗效分析[摘要]目的评价米索前列醇、硫酸镁联合应用治疗妊娠高血压综合征产后出血的临床疗效。方法方便选取该院于2015年12月—2017年9月收治的84例妊娠高血压综合征患者,随机分为对照组和联合组,每组42例,分别予以两组患者硫酸镁治疗和米索前列醇、硫酸镁联合治疗,比较两组患者治疗前、后的血压状况、产后2h、24h出血量和药物不良反应情况。结果两组患者治疗前的MAP(平均动脉压)比较差异无统计学意义(P>0.05),联合组治疗后的MAP为(85.27±4.92)mmHg,低于对
2、照组的(91.60±5.33)mmHg(t=3.903,P=0.000<0.05)。联合组产后2h、24h的出血量分别为(179.26±36.05)mL、(240.25±37.18)mL,少于对照组的(212.10±35.37)mL、(317.49±43.08)mL(t=3.910,6.070,P=0.006,0.000<0.05)。兩组药物不良反应发生率分别为7.14%、4.16%,差异无统计学意义(χ2=0.213、P=0.645>0.05)。结论米索前列醇、硫酸镁联合应用治疗妊娠高血压综合征产后出血,能够控制患者血压,减
3、少患者产后出血量,疗效可靠,不良反应少。[关键词]米索前列醇;硫酸镁;妊娠高血压综合征;产后出血[中图分类号]R714.246[文献标识码]A[文章编号]1674-0742(2018)07(a)-0122-03EffectofMisoprostolCombinedwithMagnesiumSulfateonPostpartumHemorrhageinPregnancy-inducedHypertensionZENGYu-lingDepartmentofObstetricsandGynecology,ChengdongBranc
4、h,PengyiMemorialHospital,Haifeng,GuangdongProvince,516400China[Abstract]ObjectiveThispapertriestoevaluatetheclinicalefficacyofmisoprostolandmagnesiumsulfatecombinedwithpostpartumhemorrhageinpregnancyinducedhypertension.Methods84casesofpregnancy-inducedhypertensionsy
5、ndromeadmittedtothehospitalfromDecember2015toSeptember2017wereconvenientselectedandrandomlydividedintothecontrolgroupandthecombinedgroup.Therewere42casesineachgroup.Eachgroupreceivedmagnesiumsulfatetreatmentandmisoprostol,magnesiumsulphatecombinedtreatment,comparedt
6、hebloodpressurebeforeandaftertreatmentinthetwogroupsofpatients,postpartum2h,24hbleedingandadversedrugreactions.ResultsTherewasnosignificantdifferenceinMAP(meanarterialpressure)beforetreatmentbetweenthetwogroups(P>0.05).TheMAPaftercombinedtreatmentwas(85.27±4.92)mmHg
7、,whichwaslowerthanthatofthecontrolgroup(91.60±5.33)mmHg(t=3.903,P=0.000<0.05).Thebloodlossofthecombinedgroupat2hand24hpostpartumwas(179.26±36.05)mLand(240.25±37.18)mL,respectively,lessthanthatofthecontrolgroup(212.10±35.37)mLand(317.49±43.08)mL(t=3.910,6.070,P=0.006
8、,0.000<0.05).Theincidenceofadversedrugreactionsinthetwogroupswas7.14%and4.16%,respectively,andthedifferencewasnotstatisticallysignificant(
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