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1、健脾补肾丸干预治疗糖耐量减低68例临床观察作者:辛雪香单位:汕头大学医学院第二附属医院中医科,广东汕头515041【摘要】目的探讨健脾补肾丸干预治疗糖耐量减低(1GT)患者的临床疗效。方法选择136例1GT患者,随机分为2组,在坚持饮食控制,加强运动的基础上,治疗组68例应用白拟健脾补肾丸T预治疗,对照组68例口服施尔康、复合维生素B、复方丹参滴丸。2组疗程均为4个月,观察2组治疗前后及停药6个月后空腹血糖(FPG)、餐72h血糖(2hPG)、糖化血红蛋白(HbAlc)、总胆固醇(TC)、由11三酯(TG)。结果
2、治疗组治疗前后及2组治疗后FPG、2hPG、HbAlc、TC、TG比较差异均有统计学意义(P<0.05,P<0.01);治疗组显效率及总有效率均显著高于对照组(P<0.05)o结论健脾补肾丸对IGT干预治疗疗效佳,能改善糖代谢;降低餐后血糖及降低血脂有显著效杲,对以有效截断扭转糖尿病的形成和发展。【关键词】健脾补肾丸;葡糖耐受不良;廿油三酯类;胆固胛Clinicalobservationon68casesofimpairedglucosetoleranceinterventiontreatedb
3、yJianpibushenpillXINXuex-iangDepartmentofTraditionalChineseMedicine,TheSecondAffiliatedHospitalofMedicalSchool,ShantouUniversity,Guangdong,Shantou515041[Abstract]ObjectiveToobservethetherapeuticeffectofJianpibushenpill(JPBSP)onimpairedglucosetoler-ance(IGT)pa
4、tients.Methods136casesofIGTwererandomlydividedintotwogroups,besidesthesameconventionalofdietcontrolandimprovecampaignweregiventobothgroups,JPBSPweregiventothetreatmentgroup,andTheragran,mulvitaBandsalviacomplexmiltiorrhizadrippingpillsweregiventothecontrolgro
5、up.Thetherapeuticcoursewas4monthsinbothgroups.Theleveloffastingplasmaglucose(FPG),2-hourpostprandialplasmaglucose(2hPG),hemoglobinAlc(HbAlc),totalcholesterol(TC)andtriglyeride(TG)wasdetectedbeforeandafterthetreatment,and6monthsafterthetreatmentisfinished.Resu
6、ltsTherewassignificantdifferencebetweenbeforeandaftertreatmentintreatedgroup,andtherewassignificantdifferencebetweenthetwogroupsaftertreatment.ThelevelofFPG,2hPG,HbAlc,TC,TGde-creasedaftertreatmentintreatmentgroups,showedsignificantdifferenceascomparedtothose
7、beforetreatment(P<0.05),thetotaleffectiverateandmaikedlyeffectiverateintreatmentgroupwerehigherthanthoseinthecontrolgroup(P<0.05).ConclusionJPBSPisofsignificanceeffectonIGT,itcanimproveglycometabolism,decreasepost-prandialplasmaglucoseandbloodlipid,then
8、cutofftheformationanddevelopmentofdiatetesmellitus.[Keywords]Jianpibushenpill;Impairedglucosetolerance;Triglyceride;Totalcholesterol空腹血糖(FPG)在6.1〜6.9mmol.L及糖负荷后2h血糖(2hPG)在7.9〜Ilmmol.L称Z为糖