PFOS Lecture 6 Muscular Tissue I and II

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1、MuscularTissueI(PFOS1-25)MuscularTissueII(PFOS1-26)Prof.AlisaShumSchoolofBiomedicalSciencesObjectives:xTounderstandhowmuscleisclassifiedhistologicallyandthefunctionofdifferenttypesofmusclexTounderstandthecontractionmechanismofdifferenttypesofmusclexTounderstandthegrowth®enerativecapa

2、cityofdifferenttypesofmuscleMuscletissuexMusclecells-contractionxConnectivetissue-harnessesthepullproducedbymusclecells-conveysnervefibres,bloodvesselsandlymphaticsThreetypesofmusclexSkeletalmuscle-skeletonassociated(voluntary)xCardiacmuscle-heart(involuntary)xSmoothmuscle-bloodvessels,

3、hollowortubularorgans(involuntary)ComparativefeaturesxShape&sizeofcellxNumber&locationofnucleixCelljunctionsxContractionmechanismxNervousregulationxGrowth®enerationSkeletalmusclefibre(LS)(XS)xLong,cylindricalxFusionofmyoblastsomusclefibrexMultinucleixPeripheralnucleiStructuralorganiz

4、ationofmuscleMusclefibreMusclebundle/fascicleMuscle(XS)Nocelljunctionbetweenmusclefibres(LS)xConnectivetissuesheathsurroundingindividualmusclefibreHighlyvascularizedConnectivetissuesheathsPerfusedwithreddyetoshowsurroundingskeletalmusclecapillarieswithinconnectivefibreswerestainedgreent

5、issuesheathsxSupplyoxygen&nutrientstomusclefibres-metabolicallyveryactive-requireenergyforcontractionConnectivetissuesheathxEndomysium-surroundindividualmusclefibrexPerimysium-surroundmusclebundlexEpimysium-outermostlayerofmuscle(XS)SkeletalmuscleattachestoboneviatendonTendonxTendon–fus

6、ionofconnectivetissuesheathsTendonFibroblast(LS)xDenseregularconnectivetissuexFibroblastsinrowSkeletalmuscleattachedtoskeletonxCoveredbyepimysiumxMusclebundlesarrangeparalleltooneanotherwithinthemusclexMovementinonedirectionSkeletalmusclebundleswithinorganxNoepimysiumxMusclefibresarrang

7、edinLipbundlesrunningindifferentplanesxFacilitatemovementindifferentdirectionsTongueStriatedmuscleStriatedmuscleDarkband(A)Lightband(I)ZlineMusclefibre(LS)nucleus(LS)xCrossstriationsinlongitudinalsectionxAlternatingdark(A)andlight(I)bandsxAdarkline(Zline)inmiddleoflightbandMusc