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1、细辛脑联合多索茶碱治疗AECOPD疗效观察于浩(贵州省贵阳市乌当区人民医院贵州贵阳550018)【摘要】目的：探讨细辛脑联合多索茶碱治疗AECOPD的临床疗效，并总结临床经验。方法：从2014年01月至2015年01月期间来我院内科进行治疗的AECOPD患者中随机抽取120例，平均分为对照组和观察组。其中对照组采用多索茶碱进行治疗。观察组在多索茶碱治疗的基础上联合细辛脑进行治疗。评价两组患者不同治疗后的治疗总有效率以及不良反应发牛率情况。结果：两组患者不同治疗以后，观察组患者发热改善率为97.19%,咳嗽咳痰症状改善率为89.
2、91%,喘息症状改善率为82.36%。肺部罗音改善概率为90.13%,均优于对照组(P<0.05)；观察组患者的显效率为35.78%,有效率为59.91%,治疗总有效率为95.69%,均明显高于对照组(P<0.05)；观察组患者的不良反应发生率为3.33%,明显低于对照组(P<0.05)o以上差异均具有统计学意义。结论：细辛脑联合多索茶碱治疗慢性阻塞性肺疾病急性加重期AECOPD的临床疗效显著，安全性高且不良反应的发牛概率低，值得临床推广应用。【关键词】细辛脑；多索茶碱；AECOPD；临床观察；【中图分类号】R563【文献标识
3、码】B【文章编号】1003-5028(2015)7-0040-01AsaronejointAECOPDdoxofyllinetreatmentcurativeeffectobservation[Abstract】Objective:tostudythejointasaronedoxofyllinethetreatmentofAECOPDclinicalcurativeeffect,andsummarizetheclinicalexperience.Methods:fromjan2014tojan2015toourhospita
4、lformedicaltreatmentofAECOPDrandomly120cases,dividedintocontrolgroupandobservationgroup,onaverage.ThecontrolgroupUSESthedoxofyllinetreatment.Observationgrouponthebasisofdoxofyllinetreatmentcombinedasaronefortreatment.Evaluationoftwodifferentgroupofpatientsaftertotal
5、effectivetreatmentandtheincideneeofadversereactions.Results:Twodifferentgroupofpatientsaftertreatment,theobservationgroupofpatientswithfeverperiodwas97.19%,thesymptomsofcoughandexpectorationperiodwas89.91%,thesymptomsofbreathingperiodwas82.36%.Lungraleimprovetheprob
6、abilityof90.13%,werebetterthancontrolgroup(P<0.05)；thetotaleffectiverateofthetreatmentofpatientswithobservationgroup%,significantlyhigherthanthecontrolgroup(P<0.05);Observationgroupofpatientstheincideneeofadversereactionsfor3.33%,significantlylowerthanthecontr
7、olgroup(P<0.05).Conclusion:asaronejointdoxofyllinethetreatmentofchronicobstructivepulmonarydiseasewithacuteaggravatingperiodofAECOPDclinicalcurativeeffectisdistinct,,highsafetyandlowprobabilityofoccurreneeofadversedrugreactions(adrs),worthyofclinicalpopularizatio
8、nandapplication.[keywords]：asarone;Doxofylline;AECOPD；Clinicalobservation;慢性阻塞性肺疾病(chronicobstructivepulmonarydisease,COPD),是—-种破坏性的肺部疾病。慢
