抑郁症的中医辩证治疗研究

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1、抑郁症的中医辨证治疗研究给药方法六种证型均为汤药，1N／日，2次／同。肝郁气滞证以逍遥散加减、痰火郁结证以柴芩黄连温胆汤加减、心脾两虚证以归脾汤加减、心血虚证以天王补心丹加减、心胆气虚证以安神定志丸加减、心肾不交证以酸枣仁合交泰丸加减。中医证候疗效判定标准采用尼莫地平法。临床控制：临床症状、体征消失或基本消失，证候积分减少990％；显效：临床症状、体征明显改善，证候积分减少≥70％；有效：临床症状、体征均有好转，证候积分减少>／30％；无效：临床症状、体征无明显改善，甚或加重，证候积分减少不足30％。经统计

2、学处理，结果显示周绍华导师治疗抑郁证各证型均有良好的疗效。临床控制及显效率可达2050％，总有效率可达80％以上，尤其是肝郁气滞证临床控制及显效率达到50％左右，肝郁气滞证和痰火郁结证的疗效明显优于心脾两虚证。同时，受试者的Hamilton抑郁量表积分也有明显改善，患者通过治疗8周，病情较多改善。结论本临床观察证实了中医治疗抑郁症有良好的疗效，尤其是通过辨证论治，可以更好地发挥中医药在治疗抑郁症的作用。现代抑郁症剧增、西药的副作用巨大的情况下，本研究结果说明中医抑郁症治疗具有很大的优势。抑郁症中医辨证并不仅

3、限于六种证型，对于其它证型的观察和具体加减用药还有待于进一步的研究。关键词抑郁症郁证辨证论治肝郁气滞3抑郁症的中医辨证治疗研究AbstractDepressionisamoodtosignificantandlastingchangeasthebasicclinicalmanifestationsofmentalillness，oftenaccompaniedacorrespondingchangeinthinkingandbehavior．Ashumandiseasespectrumofchangeand

4、thechangeoflife．theincidenceofdepressionincreasedyearbyyear，asystemofoneofthemostconllllondisease，aseriousthreattopeople’Shealthandlife，leadingtoserioussocialandeconomicburden，thereforethetreatmentofdepressionastheworld’Sfocus．TheWorldHealthOrganization(WH

5、O)releasedtheinformation．theexistingdepressionpatientsaroundtheworldabout340million，theprevalenceratefrom3to5percentannuallyduetomentalillnesscausedbythesuicidedeathtoll1millionandisexpectedto2020depressionwillbecometheFollowingischemicheartdiseaseafterthe

6、second-largestburdenofdisease．ThecomplexcausesofdepressionalsoCannotbeidentifiedSOfar．moreconsistentviewisthattheincidenceofbiologicalfactorsconstitutesaqualityortendency，psychologicalandsocialfactorsplayaroleintriggeringthemedia．Westernmedicinethatpatholo

7、gicalchangesofmajordepressionandcentralnervoussystem，immuneandneuroendocrinefunctionrelatedtotheexactpathogenesisisnotclear．Atpresent，amonoaminehypothesis，thehypothesisofneurotransmitterreceptors，neuroendocrinefunctionhypothesis，thehypothesisoftheimmunesys

8、temabnormalitiesandotherdisputes．Currentlyinclinicalcommonlyusedantidepressantdrugs，includingtricyclic，theFourthRingcategory，neurotransmitterinhibitors，monoamineoxidaseinhibitorsandotherdrugs．However，duetosid