骨质疏松症的影响因素和他汀类药物对该病疗效的流行病学分析

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1、Abstractlovesports，eatmilk，ofteneatgreenvegetable，lateageatnaturalmenopausehadprotectiveeffects，ORvaluesrangewereatO．134toO．732；(4)Throughmultivariatelogisticregression，therewerenodistinguishedinteractionbetweenofen“11l【milkandsports，smokingandjobproperty．(5)28literatureshadbeenchoseninMetaanalysis

2、，including9case-controlstudy,11cohortstudyand8RCT,atotalof285434subjectsfrom14differentcountrieswereincluded；(6)Comprehensiveandquantitativeresultsforincludingliteraturessuggestedthatcomparedwithcontrolgroup，statingrouphadsignificantdifferenceinimprovingBMDvaluesinfemoralneckWMD=0．02，95％CI(0．01，0．0

3、3)andreducinghipfracturetotalOR=0．50，95％CI(0．47，0．54)，increasingserumboneformationmarkerBGPcontent．SlVlD=O．93，95％CI(0．10，1．76)；whilelargerdoseuseofstatins，itmayincreaseserumboneabsorptionmarkerCTxcontent，SMD=I．12，95％CI(0．05，2．19)，wefoundnosinnific．antsignificantdifferenceinimprovingBMDvalueinlumbar

4、spine，Z=0．76，P=0．45．Conclusion：(1)Bymultivariatescreening，fourofriskfactorsinOPweresmoking，mainlyengagedinmentallabor,ofteneatanimalprotein，brinishfishandsaltedvegetable；fiveprotectivefactorswerehavinghealthyspouses，highereducationlevel，lovesports，ofteneatgreenvegetablesandmilk；(2)Thestudyinwomensu

5、ggestedthatexceptcommonriskfactorsinmaleandfemalegroup，theriskofmanygravidityorparityhistory，andlateofmenarcheshouldarouseattention；meanwhile，thestudyalsoshowedthattherearefiveprotectivefactorsinwomen．theywerehavinghealthyspouses，lovesports，eatmilk，ofteneatgreenvegetableandlateageatnaturalmenopause

6、．OPwasachronicdiseaseoccurredinmiddle-agedandtheelderlypopulation，itsincidence(prevalence)Wasaffectedbymanyfactors，theetiologyofOPiscomplex，OurstudyprovidedmeaningfulreferenceforcomprehensivepreventionofOP．Suchasincreaseselfhealthcareconsciousness，createreasonabledietandlifestyle，advocatebeneficial

7、behaviorandcalciumsupplementareimportant；Asforwomen，besidesreducethetimesofgravidityorparity,shortentheperiodoflactationproperly,keepcalciumcontent，payattentiontoendocrinesecretionmetabolismafternaturalmeno