右美托咪定对甲状腺手术颈丛阻滞麻醉患者心率变异性的影响.pdf

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1、·临床麻醉·2013年1O月第51卷第29期右美托咪定对甲状腺手术颈丛阻滞麻醉患者心率变异性的影响王宇川江西省鹰潭市人民医院麻醉科．江西鹰潭335000【摘要】目的探讨右美托咪定对甲状腺手术颈丛阻滞麻醉患者心率变异性的影响。方法选择择期行甲状腺次全切或全切手术的甲状腺瘤或甲状腺肿患者50例，随机分为观察组和对照组各25例。观察组将右旋美托咪定以1．0txg／kg在术前15min静脉泵注，对照组以相同容量生理盐水术前静脉注入。于麻醉前(T。)、切皮时(T．)、分离腺体(T：)、缝合皮肤(1r3)各点分

2、别记录各组患者心率(HR)、HRV参数值作为观察指标。结果观察组患者各时间点HR变化及HF、LF无显著差异(P>0．05)，而对照组差异显著(P

3、3—9701(2013)29—0098—02EffectofdexmedetomidineonheartratevariabilityofthyroidsurgerycervicalplexusblockinganesthesiapatientsWANGYuchuanDepartmentofAnesthesiology，YingtanPeopleSHospitalinJiangxiProvince，Yingtan335000，China[Abstract]ObjectiveToinvestigate

4、theeffectsofdexmedetomidineontheheartratevariability(HRV)inpatientssufferedwiththyroidsurgerybycervicalplexusanesthesia．MethodsAtotalof50patientsdiagnosedtothyromaandthyroncussufferedwithsubtotalortotalthyroidectomywerebeenchosenanddividedintotwogroups

5、randomly，eachof25cases．Thepatientsinobservationgroupwereacceptedwithdexmedetomidinebyintravenousinfusion1．0~g／kgat15minbeforetheoperation．Thepatientsincontrolgroupwereacceptedwiththesamevolumeofnormalsalinebyintravenousinjection．Theindexesofheartrate(H

6、R)andHRVparametersintwogroupswererecordedatbeforeanesthesiaCro)，skinincisionD，isolatedglands2)，skinsuture3)．ResultsTheindexesofHR，HFandLFinobservationgroupwerenodifferentamongfourtime-points(尸>0．05)，buttheindexesofHR，HFandLFincontrolgroupweredifferenta

7、mongfourtime-points(P<0．05)．Comparedtocontrolgroup，theindexesofHTP,HFandLFinobservationgroupweredifferentatT1，Tstime-point(P

8、nseintheoperation，maintenanceofHRVapproximatelevelbeforeanesthesia；especiallyforpatientswithcardiovascularsystemdamagearemoreusefu1．[Keywords]Dexmedetomidine；Thyroid；Cervicalplexusblock；Heartratevariability心率变异性(HRV)对心血管疾病的早期诊断、病中监1资料与方