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1、Reviewarticle541Severeacutepancreatitis:advancesandinsightsinassessmentofseverityandmanagementGiuseppeBrisinda,SerafinoVanella,AnnaCrocco,AndreaMazzari,PasquinaTomaiuolo,FrancescoSantullo,UgoGrossiandAntonioCrucittiThepatientswithacutepancreatitisareatrisktodevelopevolutionofthediseaseafewdaysfro
2、monset.EurJdifferentcomplicationsfromongoingpancreaticGastroenterolHepatol23:541–551c2011WoltersKluwerinflammation.Often,thereisnocorrelationbetweentheHealth
3、LippincottWilliams&Wilkins.degreeofstructuraldamagetopancreasandclinicalEuropeanJournalofGastroenterology&Hepatology2011,23:541–551manifest
4、ationofthedisease.TheeffectivenessofanytreatmentisrelatedtotheabilitytopredictseverityKeywords:enteralfeeding,fluidreplacement,multiorganfailuresyndrome,multiparametricscores,severeacutepancreatitis,surgicalandaccurately,butthereisnoidealpredictivesystemorinterventionaldebridementbiochemicalmarke
5、r.SeverityassessmentisindispensableDepartmentofSurgery,CatholicSchoolofMedicine,UniversityHospitaltotheselectionofproperinitialtreatmentintheAgostinoGemelli,Rome,Italymanagementofacutepancreatitis.TheuseofCorrespondencetoGiuseppeBrisinda,MD,DepartmentofSurgery,Universitymultiparametriccriteriaand
6、theevaluationofseverityindexHospitalAgostinoGemelli,LargoAgostinoGemelli8,Rome00168,Italypermitustoselecthigh-riskpatients.Furthermore,Tel:+390630154199;fax:+390630156086;e-mail:gbrisin@tin.itcontrast-enhancedcomputedtomographicscanningandcontrast-enhancedMRIplayanimportantroleinseverityAllauthor
7、scontributedequallytothewritingofthisarticleassessment.TheadoptionofmultiparametriccriteriaReceived26January2011Accepted17March2011proposedtogetherwithmorphologicalevaluationconsentstheformulationofadiscreetlyreliableprognosisontheIntroductionmanagementofsterilenecrosishasbeenintroduced,Acutepanc
8、reatitis(AP)isthethirdmostcommonapplyingearlyantibiotictreatment[6,14–16].Patientsdiagnosisatdischargeforgastrointestinaldiseases[1–3].withSAPshouldbenursedinacriticalcaresetting,asAPispredominantlycausedbysymptomaticg
