28.Current investigations on carbon nanotubes for biomedical application.pdf

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1、HomeSearchCollectionsJournalsAboutContactusMyIOPscienceCurrentinvestigationsintocarbonnanotubesforbiomedicalapplicationThisarticlehasbeendownloadedfromIOPscience.Pleasescrolldowntoseethefulltextarticle.2010Biomed.Mater.5022001(http://iopscience.iop.org/1748-605X/5/2/

2、022001)Viewthetableofcontentsforthisissue,orgotothejournalhomepageformoreDownloaddetails:IPAddress:162.105.247.87Thearticlewasdownloadedon09/12/2011at10:44Pleasenotethattermsandconditionsapply.IOPPUBLISHINGBIOMEDICALMATERIALSBiomed.Mater.5(2010)022001(12pp)doi:10.108

3、8/1748-6041/5/2/022001TOPICALREVIEWCurrentinvestigationsintocarbonnanotubesforbiomedicalapplicationXiaomingLi1,3,YuboFan1andFumioWatari21KeyLaboratoryforBiomechanicsandMechanobiologyofMinistryofEducation,SchoolofBiologicalScienceandMedicalEngineering,BeihangUniversit

4、y,Beijing100191,PeoplesRepublicofChina2DepartmentofBiomedicalMaterialsandEngineering,GraduateSchoolofDentalMedicine,HokkaidoUniversity,Sapporo060-8586,JapanE-mail:x.m.li@hotmail.comReceived29October2009Acceptedforpublication26February2010Published25March2010Onlineats

5、tacks.iop.org/BMM/5/022001AbstractThenano-dimensionalityofnaturehaslogicallygivenrisetotheinterestinusingnanomaterialsinthebiomedicalfield.Currently,alotofinvestigationsintocarbonnanotubes(CNTs),asoneofthetypicalnanomaterials,arebeingmadeforbiomedicalapplication.Inthi

6、sreview,fiveparts,suchascellularfunctionsinducedbyCNTs,apatiteformationonCNTs,CNT-basedtissueengineeringscaffold,functionalizedCNTsforthedeliveryofgenesanddrugsandCNT-basedbiosensors,arestated,whichmightindicatethatCNTs,witharangeofuniqueproperties,appearsuitedasabiom

7、aterialandmaybecomeausefultoolfortissueengineering.However,everythinghastwopartsandCNTsisnotanexception.TherearestillconcernsaboutcytotoxicityandbiodegradationofCNTs.ChemicalfictionalizationmaybeoneoftheeffectivewaystoimprovethedisadvantagesandutilizetheadvantagesofCN

8、Ts.Oneoftheirdisadvantages,unbiodegradableproperty,maybeutilizedbycreatingmonitorsininvivo-engineeredtissuesornanosizedCNT-basedbio