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1、M™ethodsinMolecularBiologySeriesEditorJohnM.WalkerSchoolofLifeSciencesUniversityofHertfordshireHatfield,Hertfordshire,AL109AB,UKForfurthervolumes:http://www.springer.com/series/7651wwwwwwwwwwwwCancerCytogeneticsMethodsandProtocolsSecondEditionEditedbyLyndaJ.Camp
2、bellVictorianCancerCytogeneticsService,St.Vincent’sHospitalMelbourne,Fitzroy,VIC,AustraliaEditorLyndaJ.CampbellVictorianCancerCytogeneticsServiceSt.Vincent’sHospitalMelbourneFitzroy,VIC,Australialynda.campbell@svhm.org.auISSN1064-3745e-ISSN1940-6029ISBN978-1-617
3、79-073-7e-ISBN978-1-61779-074-4DOI10.1007/978-1-61779-074-4SpringerNewYorkDordrechtHeidelbergLondonLibraryofCongressControlNumber:2011922375©SpringerScience+BusinessMedia,LLC2011Allrightsreserved.Thisworkmaynotbetranslatedorcopiedinwholeorinpartwithoutthewritten
4、permissionofthepublisher(HumanaPress,c/oSpringerScience+BusinessMedia,LLC,233SpringStreet,NewYork,NY10013,USA),exceptforbriefexcerptsinconnectionwithreviewsorscholarlyanalysis.Useinconnectionwithanyformofinformationstorageandretrieval,electronicadaptation,comput
5、ersoftware,orbysimilarordissimilarmethodologynowknownorhereafterdevelopedisforbidden.Theuseinthispublicationoftradenames,trademarks,servicemarks,andsimilarterms,eveniftheyarenotidentifiedassuch,isnottobetakenasanexpressionofopinionastowhetherornottheyaresubjectt
6、oproprietaryrights.Printedonacid-freepaperHumanaPressispartofSpringerScience+BusinessMedia(www.springer.com)PrefaceThisbookcomprisesaseriesofchaptersdescribingconventionalcytogeneticanalysismethods,fluorescenceinsituhybridizationandarraymethods.Allofthesetechniq
7、ueshavebeenpresentedinthecontextoftheiruseinthediagnosisandinvestigationofdifferentvarietiesofcancer.Theauthorsofthedifferentchaptershaveprovidedbothstandardmethodsandalsoextensivenotestoguideindividualswhoarenewtothesemethodsthroughthepitfallsthatbedevilallsuch
8、testing.Theexperienceoftheauthorsshouldenablealltestingtobereadilytransferable.Inevitably,therearesomeareasofrepetitionasthemethodsforpreparingchromosomesforanalysisi