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1、电针对脑卒中后抑郁大鼠单胺类递质的影响型对照组比较，差异有极显著性(P＜0.01)，作用优于非穴位针刺。结论：1.采用Zealonga线栓法结合应激刺激加孤养、束缚制动的方法可成功制备脑卒中后抑郁大鼠模型。2.电针可影响大鼠治疗前后体重，导致行为学和脑组织单胺类神经递质含量变化。关键词：电针；脑卒中后抑郁大鼠；单胺类递质；应激刺激2摘要Influenceofelectricforpost-strokedepressionmonoamineneurotransmittersinratsLiuHua(ScienceofAcupunctureandTuina)DirectedbyFanJun
2、mingAbstractObjective:Throughtheresearchondepressionaftercerebralapoplexyelectricinratsandbehaviorandweightbeforeandafterthetreatmentofmonoaminetransmittersbrain,thispaperdiscussestheinfluencesondepressionaftercerebralapoplexycuppingtreatmentmechanismofaction.Methods:①ChoosemaleSDrats,Zealongali
3、neforreferencetoboltlegalsystemmodelcerebralischemiainrats.②Thefirstfourdays,referenceoperationPerssonlevelclassificationmethodforneurologicgrading.SelectⅡ~Ⅳlevelcerebralischemiainratsasstrokemodelanimals,aregroupedputtingthemintomicecage24hsinglecageeverywillraise,loneratlimbsandheadisfixedtoth
4、especialholderbraking2h,continuous21days,copyPSDmodel.③Thefirstfourdays,willoperationratmodelsrandomlydividedintomodelcontrolgroup,cuppingtreatmentgroup,thecontrolgroup,theothersetpointsofnormalcontrolgroup.Solitaryraiseandbondagebrakingdaylinecuppingtreatment,1times/d,10min/times,continuous21da
5、ys.Chooseonstar,Shanpointsinwanandleft,st36,cuppingparametersforthecontinuouswave,frequency10Hz,wavewide0.6ms,voltage3V(1.5-withmuscleslighttwitchfordegrees).④Eachratinchronicstressexcitingday1,article8days,15days,22dayseveryotherweek,measuringweightofsucrosewaterexperiment,thewildernesstestfors
6、troke,observingelectricitydepressionafterratsweight,sugarwaterconsumption,theinfluenceofthetestscores.⑤Experimentalfirst29daysexecutedexperimentsrats,byHPLCdetectionratprefrontalcortex,hypothalamusofnorepinephrine(making),dopamine(DA),serotonin(5-HT)content.Observingelectricityforstrokeinratsdep
7、ressionaftermaking,DA,5-HTinfluence.Results:Comparedwiththecontrolgroup,weremodelratsignificantweightloss,sugarwaterconsumption,cuppingtreatmentsignificantlylowerthanthatofcontrolgroupratratacupunctureweight,sugarwaterconsum
